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1

A clash to conquer: the malaria parasite liver infection

Sebastian A. Mikolajczak, Stefan H. I. Kappe

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 372 KB

english, 2006

2

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

Ahmed S. I. Aly, Sebastian A. Mikolajczak, Hilda Silva Rivera, Nelly Camargo, Vanessa Jacobs-Lorena, Mehdi Labaied, Isabelle Coppens, Stefan H. I. Kappe

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 681 KB

english, 2008

3

Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites

Sebastian A. Mikolajczak, John B. Sacci, Jr, Patricia De La Vega, Nelly Camargo, Kelly VanBuskirk, Urszula Krzych, Jun Cao, Marcelo Jacobs-Lorena, Alan F. Cowman, Stefan H. I. Kappe

Journal:

Cellular Microbiology

Year:

2011

Language:

english

File:

PDF, 1009 KB

english, 2011

4

L-FABP is a critical host factor for successful malaria liver stage development

Sebastian A. Mikolajczak, Vanessa Jacobs-Lorena, Drew C. MacKellar, Nelly Camargo, Stefan H.I. Kappe

Journal:

International Journal for Parasitology

Year:

2007

Language:

english

File:

PDF, 624 KB

english, 2007

5

An efficient strategy for gene targeting and phenotypic assessment in the Plasmodium yoelii rodent malaria model

Sebastian A. Mikolajczak, Ahmed S.I. Aly, Ronald F. Dumpit, Ashley M. Vaughan, Stefan H.I. Kappe

Journal:

Molecular and Biochemical Parasitology

Year:

2008

Language:

english

File:

PDF, 502 KB

english, 2008

6

A dispensable Plasmodium locus for stable transgene expression

Vanessa Y. Jacobs-Lorena, Sebastian A. Mikolajczak, Mehdi Labaied, Ashley M. Vaughan, Stefan H.I. Kappe

Journal:

Molecular and Biochemical Parasitology

Year:

2010

Language:

english

File:

PDF, 716 KB

english, 2010

7

Development of humanized mouse models to study human malaria parasite infection

Vaughan, Ashley M, Kappe, Stefan HI, Ploss, Alexander, Mikolajczak, Sebastian A

Journal:

Future Microbiology

Year:

2012

Language:

english

File:

PDF, 412 KB

english, 2012

8

CD28 T cell costimulatory receptor function is negatively regulated by N-linked carbohydrates

Bruce Y Ma, Sebastian A Mikolajczak, Tetsuya Yoshida, Ryoko Yoshida, David J Kelvin, Atsuo Ochi

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 738 KB

english, 2004

9

Heme Oxygenase-1 Is an Anti-Inflammatory Host Factor that Promotes Murine Plasmodium Liver Infection

Sabrina Epiphanio, Sebastian A. Mikolajczak, Lígia A. Gonçalves, Ana Pamplona, Silvia Portugal, Sónia Albuquerque, Michael Goldberg, Sofia Rebelo, Daniel G. Anderson, Akin Akinc, Hans-Peter Vornlocher

Journal:

Cell Host & Microbe

Year:

2008

Language:

english

File:

PDF, 784 KB

english, 2008

10

A novel mitogen fusion protein against CD40+ cells with potent vaccine adjuvant properties

Tetsuya Yoshida, Ryoko Yoshida, Bruce Yong Ma, Sebastian Mikolajczak, David J. Kelvin, Atsuo Ochi

Journal:

Year:

2010

Language:

english

File:

PDF, 662 KB

english, 2010

11

Genetic engineering of attenuated malaria parasites for vaccination

Shahid M Khan, Chris J Janse, Stefan HI Kappe, Sebastian A Mikolajczak

Journal:

Current Opinion in Biotechnology

Year:

2012

Language:

english

File:

PDF, 749 KB

english, 2012

12

A transgenic Plasmodium falciparum NF54 strain that expresses GFP–luciferase throughout the parasite life cycle

Vaughan, Ashley M., Mikolajczak, Sebastian A., Camargo, Nelly, Lakshmanan, Viswanathan, Kennedy, Mark, Lindner, Scott E., Miller, Jessica L., Hume, Jen C.C., Kappe, Stefan H.I.

Journal:

Molecular and Biochemical Parasitology

Year:

2012

Language:

english

File:

PDF, 567 KB

english, 2012

13

A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene Deletion

Mikolajczak, Sebastian A, Lakshmanan, Viswanathan, Fishbaugher, Matthew, Camargo, Nelly, Harupa, Anke, Kaushansky, Alexis, Douglass, Alyse N, Baldwin, Michael, Healer, Julie, O'Neill, Matthew, Phuong,

Journal:

Molecular Therapy

Year:

2014

Language:

english

File:

PDF, 6.92 MB

english, 2014

14

Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection

Kaushansky, Alexis, Ye, Albert S., Austin, Laura S., Mikolajczak, Sebastian A., Vaughan, Ashley M., Camargo, Nelly, Metzger, Peter G., Douglass, Alyse N., MacBeath, Gavin, Kappe, Stefan H.I.

Journal:

Year:

2013

Language:

english

File:

PDF, 713 KB

english, 2013

15

Rat PSP94 Inhibits the Growth and Viability of the Rat Adenocarcinoma Cell Line PAIII In Vitro

Cadieux, Peter A., Mikolajczak, Sebastian A., Reeves, Jonathan, Strathdee, Craig, Reid, Gregor, Panchal, Chandra J., Clarke, Michael W.

Journal:

Cancer Investigation

Year:

2006

Language:

english

File:

PDF, 4.44 MB

english, 2006

16

Perturbations of Plasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility

Lindner, Scott E., Mikolajczak, Sebastian A., Vaughan, Ashley M., Moon, Wonjong, Joyce, Brad R., Sullivan, William J., Kappe, Stefan H. I.

Journal:

Cellular Microbiology

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

17

Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections

Kaushansky, Alexis, Mikolajczak, Sebastian A., Vignali, Marissa, Kappe, Stefan H. I.

Journal:

Cellular Microbiology

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

18

Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites

Douglass, Alyse N, Kain, Heather S, Abdullahi, Marian, Arang, Nadia, Austin, Laura S, Mikolajczak, Sebastian A, Billman, Zachary P, Hume, Jen C C, Murphy, Sean C, Kappe, Stefan H I, Kaushansky, Alexis

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

19

Susceptibility to Plasmodium yoelii Preerythrocytic Infection in BALB/c Substrains Is Determined at the Point of Hepatocyte Invasion

Kaushansky, Alexis, Austin, Laura S., Mikolajczak, Sebastian A., Lo, Fang Y., Miller, Jessica L., Douglass, Alyse N., Arang, Nadia, Vaughan, Ashley M., Gardner, Malcolm J., Kappe, Stefan H. I., Adams,

Journal:

Infection and Immunity

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

20

Plasmodium vivax Liver Stage Development and Hypnozoite Persistence in Human Liver-Chimeric Mice

Mikolajczak, Sebastian A., Vaughan, Ashley M., Kangwanrangsan, Niwat, Roobsoong, Wanlapa, Fishbaugher, Matthew, Yimamnuaychok, Narathatai, Rezakhani, Nastaran, Lakshmanan, Viswanathan, Singh, Naresh,

Journal:

Cell Host & Microbe

Year:

2015

Language:

english

File:

PDF, 2.31 MB

english, 2015

21

A Genetically Attenuated Parasite Vaccine Does Not Require Liver Stage Persistence to Elicit Sterile Protective Immunity against Sporozoite‐Induced Malaria in Mice

Mikolajczak, Sebastian A., Vaughan, Ashley M., Soliman, Joanne M. B., Kappe, Stefan H. I.

Journal:

The Journal of Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 376 KB

english, 2010

22

Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria

Nacer, Adela, Movila, Alexandru, Baer, Kerstin, Mikolajczak, Sebastian A., Kappe, Stefan H. I., Frevert, Ute, Riley, Eleanor M.

Journal:

Year:

2012

Language:

english

File:

PDF, 12.32 MB

english, 2012

23

Cyclic GMP Balance Is Critical for Malaria Parasite Transmission from the Mosquito to the Mammalian Host

Lakshmanan, Viswanathan, Fishbaugher, Matthew E., Morrison, Bob, Baldwin, Michael, Macarulay, Michael, Vaughan, Ashley M., Mikolajczak, Sebastian A., Kappe, Stefan H. I.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

24

Plasmodium vivax Liver Stage Development and Hypnozoite Persistence in Human Liver-Chimeric Mice

Mikolajczak, Sebastian A., Vaughan, Ashley M., Kangwanrangsan, Niwat, Roobsoong, Wanlapa, Fishbaugher, Matthew, Yimamnuaychok, Narathatai, Rezakhani, Nastaran, Lakshmanan, Viswanathan, Singh, Naresh,

Journal:

Cell Host & Microbe

Year:

2015

File:

PDF, 97 KB

2015

25

Preerythrocytic malaria vaccine development

Mikolajczak, Sebastian A, Aly, Ahmed SI, Kappe, Stefan HI

Journal:

Current Opinion in Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 112 KB

english, 2007

26

Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects

Kublin, James G., Mikolajczak, Sebastian A., Sack, Brandon K., Fishbaugher, Matt E., Seilie, Annette, Shelton, Lisa, VonGoedert, Tracie, Firat, Melike, Magee, Sara, Fritzen, Emma, Betz, Will, Kain, He

Journal:

Science Translational Medicine

Year:

2017

Language:

english

File:

PDF, 3.54 MB

english, 2017

27

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice

Sack, Brandon K., Mikolajczak, Sebastian A., Fishbaugher, Matthew, Vaughan, Ashley M., Flannery, Erika L., Nguyen, Thao, Betz, Will, Jane Navarro, Mary, Foquet, Lander, Steel, Ryan W. J., Billman, Zac

Journal:

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

28

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites

Gural, Nil, Mancio-Silva, Liliana, Miller, Alex B., Galstian, Ani, Butty, Vincent L., Levine, Stuart S., Patrapuvich, Rapatbhorn, Desai, Salil P., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Flemin

Journal:

Cell Host & Microbe

Year:

2018

Language:

english

File:

PDF, 9.79 MB

english, 2018

29

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and mechanisms for liver-stage differentiation in relapsing malaria

Muller, Ivo, Jex, Aaron R., Kappe, Stefan H.I., Mikolajczak, Sebastian A., Sattabongkot, Jetsumon, Patrapuvich, Rapatbhorn, Lindner, Scott, Flannery, Erika L., Koepfli, Cristian, Ansell, Brendan, Lerc

Journal:

International Journal for Parasitology

Year:

2019

File:

PDF, 1.95 MB

2019

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